Elevated Remnant-Like Particle Cholesterol Concentration
نویسندگان
چکیده
منابع مشابه
Elevated remnant-like particle cholesterol concentration: a characteristic feature of the atherogenic lipoprotein phenotype.
Patients at increased risk of coronary artery disease (CAD) frequently exhibit an atherogenic lipoprotein phenotype characterized by elevated plasma levels of both triglyceriderich lipoproteins (TRL) and small, dense LDL and low concentrations of HDL cholesterol. Recently, in a large observational study, the calculated non-HDL plasma cholesterol concentration (the sum of the cholesterol content...
متن کاملMetabolic Syndrome and Remnant-like Particle Cholesterol (RLP-C)
In recent years, a clustering of clinical abnormalities, termed “metabolic syndrome,” has been identified as conferring markedly elevated cardiovascular risk, including a 3-fold excess of coronary heart disease (1). The metabolic syndrome comprises abdominal obesity, insulin resistance, impaired glucose tolerance, hypertension, and dyslipidemia. Depending on the diagnostic criteria used, more t...
متن کاملElevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring Study.
OBJECTIVE Remnants of triglyceride-rich lipoproteins are thought to be atherogenic. A new antibody-based assay allows for the isolation of remnant-like particles (RLPs) from plasma or serum, and the subsequent measurement of RLP cholesterol (RLPC) and triglycerides (RLPTGs). We hypothesized that diabetic patients would have higher remnant levels than nondiabetic patients. DESIGN AND METHODS W...
متن کاملRemnant-like particle cholesterol and triglyceride levels of hypertriglyceridemic patients in the fed and fasted state.
Potentially atherogenic triglyceride-rich lipoprotein (TRL) remnants can be isolated and quantitated as remnant-like particles (RLP), using an immunoaffinity gel containing specific anti-human apolipoprotein A-I (apoA-I) and apoB-100 monoclonal antibodies. The aim of the present study was to determine the relationship between postprandial changes in RLP levels and changes in total serum triglyc...
متن کاملEffects of risperidone and olanzapine on remnant-like lipoprotein particle cholesterol (RLP-C) in schizophrenic patients
Second generation antipsychotics are associated with the risk of metabolic disorders such as diabetes mellitus and hyperlipidemia. Remnant-like lipoprotein particles cholesterol (RLP-C) are a known risk factor for cardiovascular events. The present study was performed to determine possible differences in fasting blood RLP-C levels between schizophrenic patients treated with risperidone as compa...
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ژورنال
عنوان ژورنال: Circulation
سال: 2004
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000125278.58527.f3